Action reprogramming in Parkinson's disease: response to prediction error is modulated by levels of dopamine.

@article{Galea2012ActionRI,
  title={Action reprogramming in Parkinson's disease: response to prediction error is modulated by levels of dopamine.},
  author={Joseph M. Galea and Sven Bestmann and Mazda Beigi and Marjan Jahanshahi and John C. Rothwell},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 2},
  pages={542-50}
}
Humans are able to use knowledge of previous events to estimate the probability of future actions. Consequently, an unexpected event will elicit a prediction error as the prepared action has to be replaced by an unprepared option in a process known as "action reprogramming" (AR). Here we show that people with Parkinson's disease (PD) have a dopamine-sensitive deficit in AR that is proportional to the size of the prediction error. Participants performed a probabilistic reaction time (RT) task in… CONTINUE READING
Highly Cited
This paper has 37 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Members of the UPDRS Development Committee

  • S Fahn, RL Elton
  • (Fahn S, Marsden CD,
  • 1987
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…