Action potential transfer at the Purkinje-ventricular junction: role of transitional cells

@article{Verkerk2001ActionPT,
  title={Action potential transfer at the Purkinje-ventricular junction: role of transitional cells},
  author={A. O. Verkerk and M. W. Veldkamp and A.C.G. van Ginneken and Ronald Wilders},
  journal={2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
  year={2001},
  volume={1},
  pages={9-12 vol.1}
}
At the Purkinje (P) - ventricular (V) junction a zone of "transitional (T)" cells is found. In the present study we investigated the role of these T cells in P-to-V conduction. Using the "model clamp" technique, an experimentally recorded rabbit P cell was coupled to a phase-2 Luo and Rudy (LR) model cell, which in turn was coupled to a strand of phase-2 LR model cells. In our experiments, the single LR model represents the T cell, while the strand of LR models represents subendocardial V cells… CONTINUE READING

Citations

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Electrical interactions between cardiac cells: what can we learn from two-cell systems?

  • Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)
  • 2003

Model clamp: a computer tool to probe action potential transfer between cardiac cells

  • 2001 Conference Proceedings of the 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
  • 2001

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