Action potential initiation and propagation: upstream influences on neurotransmission.

  title={Action potential initiation and propagation: upstream influences on neurotransmission.},
  author={G J Kress and Steven J Mennerick},
  volume={158 1},
Axonal action potentials initiate the cycle of synaptic communication that is key to our understanding of nervous system functioning. The field has accumulated vast knowledge of the signature action potential waveform, firing patterns, and underlying channel properties of many cell types, but in most cases this information comes from somatic intracellular/whole-cell recordings, which necessarily measure a mixture of the currents compartmentalized in the soma, dendrites, and axon. Because the… CONTINUE READING

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