Action potential duration restitution kinetics in human atrial fibrillation.

  title={Action potential duration restitution kinetics in human atrial fibrillation.},
  author={Byung-soo Kim and Young-Hoon Kim and G Hwang and Hui-Nam Pak and Sang Chil Lee and Wan Joo Shim and Dong Joo Oh and Y. M. Ro},
  journal={Journal of the American College of Cardiology},
  volume={39 8},
OBJECTIVES We undertook this study to determine whether human atrial fibrillation (AF) relates to steeply sloped action potential duration restitution (APDR) kinetics and whether the spatial nonuniformity of APDR promotes persistence of AF. BACKGROUND A steeply sloped APDR curve is known to be an important determinant of the induction of more complex action potential duration (APD) dynamics and fibrillation. METHODS Patients with chronic atrial fibrillation (CAF) (n = 18), paroxysmal atrial… CONTINUE READING

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