Action of vitamin A on DNA adduct formation by aflatoxin B1 in a microsome catalyzed reaction.

Abstract

The effect of vitamin A and some derivatives has been studied on the formation of DNA adduct by aflatoxin B1 (AFB1) in an in vitro reaction catalyzed by rat liver microsomes. Retinol, retinal, all trans retinoic acid and two retinyl esters were found to inhibit the adduct formation in a dose-dependent manner. The inhibition by retinol showed that it was… (More)

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@article{Firozi1987ActionOV, title={Action of vitamin A on DNA adduct formation by aflatoxin B1 in a microsome catalyzed reaction.}, author={Pervez Firoz Firozi and V. S. Aboobaker and Rajib K Bhattacharya}, journal={Cancer letters}, year={1987}, volume={34 2}, pages={213-20} }