Action of morphine on melatonin release in the rat.

@article{Esposti1988ActionOM,
  title={Action of morphine on melatonin release in the rat.},
  author={D. Esposti and G. Degli Esposti and Paolo Lissoni and L Parravicini and Franco Fraschini},
  journal={Journal of pineal research},
  year={1988},
  volume={5 1},
  pages={
          35-9
        }
}
Some data from the literature raised the possibility of an interaction between the opioidergic system and pineal secretion. The present study was undertaken in order to investigate the acute influence exerted by opioids upon plasma melatonin levels in the albino rat. Different doses of morphine hydrochloride were injected (1, 1.5, 2, 3 mg/kg) intraperitoneally into anaesthetized adult male rats bearing a cannula previously inserted into the carotid. Blood samples were collected subsequently at… CONTINUE READING

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