Action of glucosamine on acetylcholine-sensitive channels

@article{Marchais2005ActionOG,
  title={Action of glucosamine on acetylcholine-sensitive channels},
  author={D Marchais and Alain Marty},
  journal={The Journal of Membrane Biology},
  year={2005},
  volume={56},
  pages={43-48}
}
  • D Marchais, Alain Marty
  • Published 2005
  • Chemistry, Medicine
  • The Journal of Membrane Biology
  • SummaryThe action of glucosamine was studied on voltage clamped neurones ofAplysia, presenting an excitatory response to acetylcholine. Noise and relaxation experiments show that glucosamine increases the mean channel open time and reduces the amplitude of the elementary current associated with the acetylcholine response. Both effects are enhanced by hyperpolarization of the cell membrane. The results are interpreted by a model assuming glucosamine binding to open channels. This binding impedes… CONTINUE READING

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