Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects.

  title={Action of cannabidiol on the anxiety and other effects produced by delta 9-THC in normal subjects.},
  author={Ant{\^o}nio Waldo Zuardi and Isao Shirakawa and Estera Finkelfarb and I. G. Karniol},
  volume={76 3},
The object of the experiment was to verify whether cannabidiol (CBD) reduces the anxiety provoked by delta 9-THC in normal volunteers, and whether this effect occurs by a general block of the action of delta 9-THC or by a specific anxiolytic effect. Appropriate measurements and scales were utilized and the eight volunteers received, the following treatments in a double-blind procedure: 0.5 mg/kg delta 9-THC, 1 mg/kg CBD, a mixture containing 0.5 mg/kg delta 9-THC and 1 mg/kg CBD and placebo and… CONTINUE READING
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