Action of cannabidiol on the anxiety and other effects produced by δ9-THC in normal subjects

  title={Action of cannabidiol on the anxiety and other effects produced by δ9-THC in normal subjects},
  author={A. W. Zuardi and I. Shirakawa and E. Finkelfarb and I. G. Karniol},
  • A. W. Zuardi, I. Shirakawa, +1 author I. G. Karniol
  • Published 2004
  • Psychology
  • Psychopharmacology
  • The object of the experiment was to verify whether cannabidiol (CBD) reduces the anxiety provoked by Δ9-TCH in normal volunteers, and whether this effect occurs by a general block of the action of Δ9-TCH or by a specific anxiolytic effect. Appropriate measurements and scales were utilized and the eight volunteers received, the following treatments in a double-blind procedure: 0.5 mg/kg Δ9-TCH, 1 mg/kg CBD, a mixture containing 0.5 mg/kg Δ9-TCH and 1 mg/kg CBD and placebo and diazepam (10 mg) as… CONTINUE READING
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