Action of Gold Nanospikes-Based Nanoradiosensitizers: Cellular Internalization, Radiotherapy, and Autophagy.

@article{Ma2017ActionOG,
  title={Action of Gold Nanospikes-Based Nanoradiosensitizers: Cellular Internalization, Radiotherapy, and Autophagy.},
  author={Ningning Ma and Peidang Liu and Nongyue He and Ning Gu and Fu-Gen Wu and Zhan Chen},
  journal={ACS applied materials & interfaces},
  year={2017},
  volume={9 37},
  pages={
          31526-31542
        }
}
A major challenge to achieve effective X-ray radiation therapy is to use a relatively low and safe radiation dose. Various radiosensitizers, which can significantly enhance the radiotherapeutic performance, have been developed. Gold-based nanomaterials, as a new type of nanoparticle-based radiosensitizers, have been extensively used in researches involving cancer radiotherapy. However, the cancer therapeutic effect using the gold nanoparticle-based radiotherapy is usually not significant… CONTINUE READING