Action of DNA repair endonuclease ERCC1/XPF in living cells.


To study the nuclear organization and dynamics of nucleotide excision repair (NER), the endonuclease ERCC1/XPF (for excision repair cross complementation group 1/xeroderma pigmentosum group F) was tagged with green fluorescent protein and its mobility was monitored in living Chinese hamster ovary cells. In the absence of DNA damage, the complex moved freely… (More)


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@article{Houtsmuller1999ActionOD, title={Action of DNA repair endonuclease ERCC1/XPF in living cells.}, author={Adriaan B. Houtsmuller and Suzanne Rademakers and Alex L. Nigg and Deborah Hoogstraten and Janneke Hoeijmakers and Wim Vermeulen}, journal={Science}, year={1999}, volume={284 5416}, pages={958-61} }