Action mechanisms of Liver X Receptors.


The two Liver X Receptors, LXRα and LXRβ, are nuclear receptors belonging to the superfamily of ligand-activated transcription factors. They share more than 78% homology in amino acid sequence, a common profile of oxysterol ligands and the same heterodimerization partner, Retinoid X Receptor. LXRs play crucial roles in several metabolic pathways: lipid… (More)
DOI: 10.1016/j.bbrc.2013.11.077


  • Presentations referencing similar topics