Actinobacterial acyl coenzyme A synthetases involved in steroid side-chain catabolism.

Abstract

Bacterial steroid catabolism is an important component of the global carbon cycle and has applications in drug synthesis. Pathways for this catabolism involve multiple acyl coenzyme A (CoA) synthetases, which activate alkanoate substituents for β-oxidation. The functions of these synthetases are poorly understood. We enzymatically characterized four… (More)
DOI: 10.1128/JB.01012-13

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