Actinobacillus pleuropneumoniae serotype 10 derived ApxI induces apoptosis in porcine alveolar macrophages.

@article{Chien2009ActinobacillusPS,
  title={Actinobacillus pleuropneumoniae serotype 10 derived ApxI induces apoptosis in porcine alveolar macrophages.},
  author={M N Chien and You-Yu Chan and Zeng-Weng Chen and Chi-Ming Wu and J W Liao and Ter-Hsin Chen and Wei-Cheng Lee and K S Yeh and S L Hsuan},
  journal={Veterinary microbiology},
  year={2009},
  volume={135 3-4},
  pages={327-33}
}
Actinobacillus pleuropneumoniae (AP) is the causative agent of swine pleuropneumonia, a fibrinous, exudative, hemorrhagic, necrotizing pleuropneumonia affecting all ages of pigs. Actinobacillus pleuropneumoniae exotoxins (Apx) are one of the major virulence factors of AP. Due to the complex nature of Apx toxins produced by AP, little is known regarding the interactions of individual species of Apx toxin with target cells. The objective of this study was to examine whether AP serotype 10-derived… CONTINUE READING

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