Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II

@article{Hofmann2004ActinIP,
  title={Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II},
  author={W. Hofmann and L. Stojiljkovi{\'c} and B. Fuchsov{\'a} and Gabriela M. Vargas and E. Mavrommatis and V. Philimonenko and Katar{\'i}na Kysel{\'a} and J. Goodrich and J. Lessard and T. Hope and P. Hoz{\'a}k and P. Lanerolle},
  journal={Nature Cell Biology},
  year={2004},
  volume={6},
  pages={1094-1101}
}
Actin is abundant in the nucleus and has been implicated in transcription; however, the nature of this involvement has not been established. Here we demonstrate that β-actin is critically involved in transcription because antibodies directed against β-actin, but not muscle actin, inhibited transcription in vivo and in vitro. Chromatin immunoprecipitation assays demonstrated the recruitment of actin to the promoter region of the interferon-γ-inducible MHC2TA gene as well as the interferon… Expand
Molecular functions of nuclear actin in transcription
Actin and myosin in transcriptional and post-transcriptional control of gene expression
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