Actin involvement in apoptotic chromatin changes of hemopoietic cells undergoing hyperthermia

@article{Luchetti2002ActinII,
  title={Actin involvement in apoptotic chromatin changes of hemopoietic cells undergoing hyperthermia},
  author={Francesca Luchetti and Sabrina Burattini and Paola Ferri and Salvatore Papa and Elisabetta Falcieri},
  journal={Apoptosis},
  year={2002},
  volume={7},
  pages={143-152}
}
During apoptosis, cell chromatin undergoes characteristic morphological changes, which have been long described in a variety of experimental models but are mostly not yet understood. The aim of the present study was to investigate the mechanisms underlying this phenomenon and the possible role of cytoskeleton, in particular actin. The chosen apoptotic model were HL60 hemopoietic cells undergoing hyperthermia and the starting point was the observation of thin filament bundles in decondensed… CONTINUE READING