Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins

Abstract

Rat peritoneal mast cells, both intact and permeabilized, have been used widely as model secretory cells. GTP-binding proteins and calcium play a major role in controlling their secretory response. Here we have examined changes in the organization of actin filaments in intact mast cells after activation by compound 48/80, and in permeabilized cells after… (More)

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Cite this paper

@article{Norman1994ActinFO, title={Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins}, author={J C Norman and Louise Price and A. J. Ridley and Alistair Scott Hall and Anna Koffer}, journal={The Journal of Cell Biology}, year={1994}, volume={126}, pages={1005 - 1015} }