Actin dynamics in the contractile ring during cytokinesis in fission yeast

@article{Pelham2002ActinDI,
  title={Actin dynamics in the contractile ring during cytokinesis in fission yeast},
  author={R. Pelham and F. Chang},
  journal={Nature},
  year={2002},
  volume={419},
  pages={82-86}
}
Cytokinesis in many eukaryotes requires a contractile ring of actin and myosin that cleaves the cell in two. Little is known about how actin filaments and other components assemble into this ring structure and generate force. Here we show that the contractile ring in the fission yeast Schizosaccharomyces pombe is an active site of actin assembly. This actin polymerization activity requires Arp3, the formin Cdc12, profilin and WASP, but not myosin II or IQGAP proteins. Both newly polymerized… Expand
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The ARP2/3 complex prevents excessive formin activity during cytokinesis
Myosin-II-Dependent Localization and Dynamics of F-Actin during Cytokinesis
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