Actin dynamics in development of behavioral sensitization after withdrawal from long-term ethanol administration to mice.

@article{Shibasaki2012ActinDI,
  title={Actin dynamics in development of behavioral sensitization after withdrawal from long-term ethanol administration to mice.},
  author={Masahiro Shibasaki and Kazuhiro Kurokawa and Koji Mizuno and Tsutomu Suzuki and Seitaro Ohkuma},
  journal={Alcoholism, clinical and experimental research},
  year={2012},
  volume={36 8},
  pages={1385-96}
}
BACKGROUND AND METHODS The present study investigated the role of actin depolymerizing factor (ADF) in the brain of mice after withdrawal from continuous ethanol (EtOH) vapor inhalation for 9 days using C57BL/6J and ADF mutant mice. RESULTS C57BL/6J mice with withdrawal signs 10 hours after withdrawal from EtOH vapor inhalation showed transient and significant enhancement of locomotor activity by a single injection of EtOH (2 g/kg, i.p.) and of EtOH-induced place preference 3 days after… CONTINUE READING