Actin depolymerisation induces process formation on MAP2-transfected non-neuronal cells.

@article{Edson1993ActinDI,
  title={Actin depolymerisation induces process formation on MAP2-transfected non-neuronal cells.},
  author={K Edson and B Weisshaar and Andrew Matus},
  journal={Development},
  year={1993},
  volume={117 2},
  pages={689-700}
}
We have previously shown that microtubules in nonneuronal cells form long, stable bundles after transfection with the embryonic neuronal microtubule-associated protein MAP2c. In this study, we found that treating MAP2c-transfected cells with the actin depolymerising drug cytochalasin B led to the outgrowth of microtubule-containing processes from the cell surface. This effect was specific to MAP2c and did not occur in untransfected cells whose microtubules had been stabilised by treatment with… CONTINUE READING

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