Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function.

@article{Sandbo2011ActinCI,
  title={Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function.},
  author={Nathan Sandbo and Nickolai O. Dulin},
  journal={Translational research : the journal of laboratory and clinical medicine},
  year={2011},
  volume={158 4},
  pages={181-96}
}
Myofibroblasts are modified fibroblasts characterized by the presence of a well-developed contractile apparatus and the formation of robust actin stress fibers. These mechanically active cells are thought to orchestrate extracellular matrix remodeling during normal wound healing in response to tissue injury; these cells are found also in aberrant tissue remodeling in fibrosing disorders. This review surveys the understanding of the role of actin stress fibers in myofibroblast biology. Actin… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 237 references

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro

  • AB Roberts, SpornMB, RK Assoian
  • Proc Natl Acad Sci U S A 1986;83:4167–71
  • 1986
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…