Actin cytoskeleton: Thinking globally, actin’ locally

@article{Lanier2000ActinCT,
  title={Actin cytoskeleton: Thinking globally, actin’ locally},
  author={Lorene M. Lanier and Frank B. Gertler},
  journal={Current Biology},
  year={2000},
  volume={10},
  pages={R655-R657}
}
A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis. 

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