Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D.

Abstract

The present study describes a novel phenomenon in pancreatic acinar cells undergoing regulated exocytosis. When acinar cell preparations were challenged with the secretagogue carbamylcholine, a subpopulation of zymogen granules became coated with filamentous actin. These zymogen granules were always in proximity of the acinar cell apical membrane (the site… (More)

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@article{Valentijn2000ActinCO, title={Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D.}, author={Jack A. Valentijn and Karine M. Valentijn and Lisa M Pastore and James Jamieson}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2000}, volume={97 3}, pages={1091-5} }