Actin bundling: initiation mechanisms and kinetics.

@article{Kraikivski2008ActinBI,
  title={Actin bundling: initiation mechanisms and kinetics.},
  author={Pavel K. Kraikivski and Boris M. Slepchenko and Igor L. Novak},
  journal={Physical review letters},
  year={2008},
  volume={101 12},
  pages={
          128102
        }
}
Bundling of rapidly polymerizing actin filaments underlies the dynamics of filopodial protrusions that play an important role in cell migration and cell-cell interaction. Recently, the formation of actin bundles has been reconstituted in vitro, and two scenarios of bundle initiation, involving binding of two filament tips and, alternatively, linking of the tip of one filament to the side of the other, have been discussed. A first theoretical analysis is presented indicating that the two… CONTINUE READING

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