Actin associated proteins function as androgen receptor coregulators: An implication of androgen receptor's roles in skeletal muscle

@article{Ting2008ActinAP,
  title={Actin associated proteins function as androgen receptor coregulators: An implication of androgen receptor's roles in skeletal muscle},
  author={Hieng Ming Ting and Chawnshang Chang},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2008},
  volume={111},
  pages={157-163}
}
This review of androgen receptor (AR) coregulators, which also function as actin-binding proteins, intends to establish the connection between actin cytoskeletal components and androgen signaling, especially in skeletal muscle. In cellular and animal models, androgen activated AR modulates myoblasts proliferation, promotes sexual dimorphic muscle development, and alters muscle fiber type. In the clinical setting, administration of anabolic androgens can decrease cachexia and speed wound healing… CONTINUE READING
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