Actin and Actin-Binding Proteins.

@article{Pollard2016ActinAA,
  title={Actin and Actin-Binding Proteins.},
  author={Thomas D. Pollard},
  journal={Cold Spring Harbor perspectives in biology},
  year={2016},
  volume={8 8}
}
Organisms from all domains of life depend on filaments of the protein actin to provide structure and to support internal movements. Many eukaryotic cells use forces produced by actin polymerization for their motility, and myosin motor proteins use ATP hydrolysis to produce force on actin filaments. Actin polymerizes spontaneously, followed by hydrolysis of a bound adenosine triphosphate (ATP). Dissociation of the γ-phosphate prepares the polymer for disassembly. This review provides an overview… CONTINUE READING
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