Actin Mechanics and Fragmentation.

@article{Cruz2015ActinMA,
  title={Actin Mechanics and Fragmentation.},
  author={Enrique M. De La Cruz and Margaret L. Gardel},
  journal={The Journal of biological chemistry},
  year={2015},
  volume={290 28},
  pages={17137-44}
}
Cell physiological processes require the regulation and coordination of both mechanical and dynamical properties of the actin cytoskeleton. Here we review recent advances in understanding the mechanical properties and stability of actin filaments and how these properties are manifested at larger (network) length scales. We discuss how forces can influence local biochemical interactions, resulting in the formation of mechanically sensitive dynamic steady states. Understanding the regulation of… CONTINUE READING

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