Actin’ up: Herpesvirus Interactions with Rho GTPase Signaling

  title={Actin’ up: Herpesvirus Interactions with Rho GTPase Signaling},
  author={C{\'e}line Van den Broeke and Herman W. Favoreel},
Herpesviruses constitute a very large and diverse family of DNA viruses, which can generally be subdivided in alpha-, beta- and gammaherpesvirus subfamilies. Increasing evidence indicates that many herpesviruses interact with cytoskeleton-regulating Rho GTPase signaling pathways during different phases of their replication cycle. Because of the large differences between herpesvirus subfamilies, the molecular mechanisms and specific consequences of individual herpesvirus interactions with Rho… CONTINUE READING

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