Act1-hsp90 heats up TH17 inflammation

Abstract

e-mail: jay.kolls@chp.edu C derived from the TH17 subset of helper T cells, especially interleukin 17A (IL-17A), IL-17F and IL-22, promote tissue inflammatory responses, as well as mucosal immunity to bacterial and fungal pathogens1. IL-22 promotes tissue regeneration2; however, both IL-17A and IL-22 have been linked to psoriasis, a disease characterized by… (More)
DOI: 10.1038/ni.2498

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