Acrylonitrile: a reevaluation of the database to support an inhalation cancer risk assessment.

@article{Felter1997AcrylonitrileAR,
  title={Acrylonitrile: a reevaluation of the database to support an inhalation cancer risk assessment.},
  author={Susan P Felter and J S Dollarhide},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={1997},
  volume={26 3},
  pages={281-7}
}
Acrylonitrile (ACN) is a monomer used extensively in the production of plastics, synthetic fibers, and rubber. In previous assessments conducted by IARC and the EPA, ACN was classified as a probable human carcinogen based on limited evidence in humans and sufficient evidence in laboratory animals. Specifically, EPA had determined that there was an association between ACN exposure and lung cancer based on a study by O'Berg (1980, J. Occup. Med. 22, 245-252). However, a follow-up of this cohort… CONTINUE READING
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