Acromegaly, growth hormone and cancer risk.

@article{Renehan2008AcromegalyGH,
  title={Acromegaly, growth hormone and cancer risk.},
  author={Andrew G Renehan and Bernadette M Brennan},
  journal={Best practice & research. Clinical endocrinology & metabolism},
  year={2008},
  volume={22 4},
  pages={
          639-57
        }
}
Acromegaly is an endocrine disorder characterized by sustained hypersecretion of growth hormone (GH) with concomitant elevation of insulin-like growth factor I (IGF-I) associated with premature mortality from cardiopulmonary diseases and certain malignancies. In particular, there is a two-fold increased risk of developing colorectal cancer. Possible mechanisms underlying this association include elevated levels of circulating GH and IGF-I, but several other plausible processes may be relevant… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 55 CITATIONS, ESTIMATED 41% COVERAGE

FILTER CITATIONS BY YEAR

2009
2018

CITATION STATISTICS

  • 1 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 96 REFERENCES

Type 2 diabetes mellitus as risk factor for colorectal cancer

  • JM Berster, B. Goke
  • Archives of Physiology and Biochemistry
  • 2008