Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine.

@article{Young2003AcquisitionON,
  title={Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine.},
  author={Heather M Young and Annette J. Bergner and T. O. M{\"u}ller},
  journal={The Journal of comparative neurology},
  year={2003},
  volume={456 1},
  pages={1-11}
}
Enteric neurons and glia arise from the neural crest. The phenotype of crest-derived cells was examined as they differentiated into neurons or glia in the mouse small and large intestine. Previous studies have shown that undifferentiated enteric crest-derived cells are Phox2b(+)/Ret(+)/p75(+)/Sox10(+), and at embryonic day (E) 10.5, about 10-15% of the crest-derived cells in the small intestine have started to differentiate into neurons. In the current study, by E12.5 and E14.5, about 25% and… CONTINUE READING
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