Acquisition of i(8q) as an early event in malignant triton tumors.

@article{Magrini2004AcquisitionOI,
  title={Acquisition of i(8q) as an early event in malignant triton tumors.},
  author={Elisabetta Magrini and Antonella Pragliola and Donatella Fantasia and Giovanni Calabrese and Alessia Gaiba and Anna Farnedi and Guido Collina and Annalisa Pession},
  journal={Cancer genetics and cytogenetics},
  year={2004},
  volume={154 2},
  pages={
          150-5
        }
}
Malignant triton tumors (MTT) are rare soft-tissue tumors characterized by a mixture of cells with nerve sheath and skeletal muscle differentiation. MTT is a histological variant of malignant peripheral nerve sheath tumors (MPNST). No characteristic cytogenetic anomaly has been detected in MPNST or MTT. In this paper, we report on the cytogenetic findings of an MTT from a 20-year old male with neurofibromatosis (NF1). The tumoral karyotype showed the modal number to be near-diploid and an… CONTINUE READING

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TP53 mutation analysis of malignant peripheral nerve sheath tumors.

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