Acquisition of Streptococcus pneumoniae and nonspecific morbidity in infants and their families: a cohort study.

@article{Sleeman2005AcquisitionOS,
  title={Acquisition of Streptococcus pneumoniae and nonspecific morbidity in infants and their families: a cohort study.},
  author={Karen L Sleeman and Lesley Daniels and Marion Gardiner and David B Griffiths and Jonathan J. Deeks and Ron Dagan and Sunetra Gupta and E . Richard Moxon and Tim E. A. Peto and Derrick W. Crook},
  journal={The Pediatric infectious disease journal},
  year={2005},
  volume={24 2},
  pages={121-7}
}
BACKGROUND Most children are believed to acquire Streptococcus pneumoniae asymptomatically, with only a few developing overt S. pneumoniae disease. This study investigates the relationship between acquisition of S. pneumoniae and mild nonspecific infection leading to general practitioner (GP) consultation. METHODS A prospective birth cohort study of 213 infants assessed at home 9 times during 24 weeks by nasopharyngeal swab and parental interview was conducted. RESULTS All positive S… CONTINUE READING

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