Acquisition and generalization of fear conditioning are not modulated by the BDNF-val66met polymorphism in humans.

@article{TorrentsRodas2012AcquisitionAG,
  title={Acquisition and generalization of fear conditioning are not modulated by the BDNF-val66met polymorphism in humans.},
  author={David Torrents-Rodas and Miquel Angel Fullana and B{\'a}rbara Arias and Albert Bonillo and Xavier Caseras and {\'O}scar Andi{\'o}n and Marina Mitjans and Lourdes Fa{\~n}an{\'a}s and Rafael Torrubia},
  journal={Psychophysiology},
  year={2012},
  volume={49 5},
  pages={713-9}
}
Few studies have investigated the role of the BDNF-val66met polymorphism in fear conditioning in humans, and previous results have been inconsistent. In the present study, we examined whether the BDNF-val66met was associated with differences in the acquisition and generalization of fear during a differential conditioning paradigm in a large sample of participants (N = 141). Using three different indexes of fear learning (fear-potentiated startle, skin conductance response, and online risk… CONTINUE READING
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Variation in the BDNF

  • C. Segalàs, J. M. . . Menchón
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