Acquired von Willebrand syndrome in aortic stenosis.

  title={Acquired von Willebrand syndrome in aortic stenosis.},
  author={Andr{\'e} Vincentelli and Sophie Susen and Thierry Le Tourneau and Isabelle Six and Olivier Fabre and Francis Juthier and Anne Bauters and Christophe Decoene and Jenny Goudemand and Alain Prat and Brigitte Jude},
  journal={The New England journal of medicine},
  volume={349 4},
BACKGROUND Aortic-valve stenosis can be complicated by bleeding that is associated with acquired type 2A von Willebrand syndrome. However, the prevalence and cause of the hemostatic abnormality in aortic stenosis are unknown. METHODS We enrolled 50 consecutive patients with aortic stenosis, who completed a standardized screening questionnaire to detect a history of bleeding. Forty-two patients with severe aortic stenosis underwent valve replacement. Platelet function under conditions of high… 

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