Acquired subglottic stenosis following prolonged endotracheal intubation. A canine model.

@article{Supance1982AcquiredSS,
  title={Acquired subglottic stenosis following prolonged endotracheal intubation. A canine model.},
  author={John S Supance and James S Reilly and William J. Doyle and Charles D. Bluestone and Jane Hubbard},
  journal={Archives of otolaryngology},
  year={1982},
  volume={108 11},
  pages={727-31}
}
We developed a canine animal model of subglottic stenosis following prolonged intubation with modified non-cuffed endotracheal tubes. None of the puppies intubated for seven days had an irreversible stenosing subglottic lesion, whereas all animals intubated for 14 days or more had at least a 40% to 50% reduction of the subglottic lumen secondary to maturing fibrotic stenosis. The model described is more congruent with the known and suspected pathogenesis in those infants and children who… CONTINUE READING

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