Acquired neuromyotonia: superiority of plasma exchange over high-dose intravenous human immunoglobulin

Abstract

Sirs: Acquired neuromyotonia (or Isaacs’ syndrome) is characterized by hyperexcitability of (sudo)motor nerves that results in continuous muscle fiber activity (myokymia), muscle cramps, weakness, and excessive sweating [1]. It has been considered a paraneoplastic syndrome with a probable autoimmune response to ion channels [1]. About 20% of cases have an… (More)
DOI: 10.1007/s004150050419

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