Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models.

@article{Shelton1999AcquiredMG,
  title={Acquired myasthenia gravis: what we have learned from experimental and spontaneous animal models.},
  author={Gloria Diane Shelton},
  journal={Veterinary immunology and immunopathology},
  year={1999},
  volume={69 2-4},
  pages={239-49}
}
Acquired myasthenia gravis (MG) is a disorder of neuromuscular transmission in which muscle weakness results from an autoantibody mediated depletion of acetylcholine receptors (AChR) at the neuromuscular junction. Experimental autoimmune myasthenia gravis, described in rodents and rabbits, has provided a good model of the effects of the autoimmune response against AChR and has shown that the specificities of the immune response in MG are those that would be obtained by immunization with native… CONTINUE READING

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