Acquired immunodeficiency syndrome and the blood-brain barrier

@article{Ivey2009AcquiredIS,
  title={Acquired immunodeficiency syndrome and the blood-brain barrier},
  author={Nathan Ivey and Andrew G MacLean and Andrew A Lackner},
  journal={Journal of NeuroVirology},
  year={2009},
  volume={15},
  pages={111-122}
}
The blood-brain barrier (BBB) plays a critical role in normal physiology of the central nervous system by regulating what reaches the brain from the periphery. The BBB also plays a major role in neurologic disease including neuropathologic sequelae associated with infection by human immunodeficiency virus (HIV) in humans and the closely related simian immunodeficiency virus (SIV) in macaques. In this review, we provide an overview of the function, structure, and components of the BBB, followed… CONTINUE READING
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