Acquired hemophilia A caused by factor VIII inhibitors: report of a case

@article{Hosoya2012AcquiredHA,
  title={Acquired hemophilia A caused by factor VIII inhibitors: report of a case},
  author={Yoshinori Hosoya and Miho Matsumura and Seiji Madoiwa and Toru Zuiki and Shiro Matsumoto and Shin Nunomiya and Alan Kawarai Lefor and Naohiro Sata and Yoshikazu Yasuda},
  journal={Surgery Today},
  year={2012},
  volume={43},
  pages={670-674}
}
We report a case of acquired hemophilia A (AHA) after esophageal resection. The patient was an 80-year-old woman whose preoperative activated partial-thromboplastin time (APTT) was well within the normal range, at 34.9 s. She underwent thoracic esophagectomy and gastric pull-up for superficial esophageal cancer (operative time, 315 min; intraoperative blood loss, 245 ml). Intrathoracic and subcutaneous bleeding occurred spontaneously on postoperative day (POD) 39. The APTT was prolonged, at 140… CONTINUE READING
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