Acquired factor VIII inhibitor in a patient with chronic myelogenous leukemia receiving interferon-alfa therapy.


OBJECTIVE To report a case of an acquired factor VIII inhibitor associated with the use of interferon-alfa. CASE SUMMARY A 58-year-old white man with newly diagnosed chronic myelogenous leukemia (CML) was initially treated with hydroxyurea. Interferon-alfa therapy was started six weeks later in order to enhance the response, with gradual reduction and… (More)


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