Acquired alpha-2-antiplasmin deficiency in acute promyelocytic leukaemia.

  title={Acquired alpha-2-antiplasmin deficiency in acute promyelocytic leukaemia.},
  author={Giuseppe Avvisati and Julia ten Cate and Auguste Sturk and R. Lamping and M G Petti and Franco Mandelli},
  journal={British journal of haematology},
  volume={70 1},
We report a prospective study in nine consecutive adult patients with acute promyelocytic leukaemia (APL). The study objective was to assess the prevalence of activation of blood coagulation and/or activation of fibrinolysis in APL. Coagulation and fibrinolytic parameters relevant to the objective included antithrombin III, plasminogen, fibrin/fibrinogen degradation products and alpha-2 antiplasmin activity and antigen levels. The results of this study revealed consistently normal antithrombin… CONTINUE READING


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