Acquired B antigen and polyagglutination in a patient with gastric cancer

  title={Acquired B antigen and polyagglutination in a patient with gastric cancer},
  author={Sho Matsushita and Takashi Imamura and T Mizuta and Motosuke Hanada},
  journal={The Japanese journal of surgery},
Erythrocytes from a patient with blood type of A1 became nongenetically reactive with A (anti-B) serum, following the development of gastric cancer. Transient polyagglutinability was also apparent. Thein vitro acetylation of the erythrocyte antigens abolished both the acquired B antigen and the polyagglutination. Although incubation of the heterologous type A1 erythrocytes with the patient's serum did not produce B antigen, deacetylase activity in the serum seems to relate to the acquired B… 

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  • Rinsho Byori XI: 6t9-623,
  • 1965
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  • Biochemistry
  • 1964