Acoustic droplet vaporization threshold: effects of pulse duration and contrast agent

@article{Lo2007AcousticDV,
  title={Acoustic droplet vaporization threshold: effects of pulse duration and contrast agent},
  author={Andrea Hsio-an Lo and Oliver D. Kripfgans and Paul L. Carson and Edward D. Rothman and J. Brian Fowlkes},
  journal={IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control},
  year={2007},
  volume={54}
}
The use of superheated liquid perfluorocarbon droplets encased in albumin shells has been proposed as a minimally invasive alternative to current treatment of cancer by means of occlusion therapy. In response to an applied acoustic field, these droplets, which are small enough to pass through capillaries, vaporize into large gas bubbles that subsequently lodge in the vasculature. This technique, known as acoustic droplet vaporization (ADV) has been shown to successfully reduce blood flow in… 
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TLDR
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Two pressure thresholds at which stabilized microbubbles undergo inertial cavitation are identified and have potential significance for both diagnostic and therapeutic ultrasound applications.
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TLDR
Acoustic droplet vaporization (ADV) has been introduced with the potential application of tumor treatment via occlusion and subsequent necrosis and currently used radiofrequency tissue ablation-based tumor treatment could benefit from ADV due to the decreased heat loss via vascular cooling.
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