Acne Pathogenesis: History of Concepts

@article{Tilles2014AcnePH,
  title={Acne Pathogenesis: History of Concepts},
  author={G{\'e}rard Tilles},
  journal={Dermatology},
  year={2014},
  volume={229},
  pages={1 - 46}
}
  • G. Tilles
  • Published 13 September 2014
  • Medicine
  • Dermatology
From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process. Although the importance of these factors has been reevaluated, recent works still regarded them as… 

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