Acidosomes: recipients of multiple sources of membrane and cargo during development and maturation.

  title={Acidosomes: recipients of multiple sources of membrane and cargo during development and maturation.},
  author={Richard D M Allen and Liping Ma and A. K. K. Fok},
  journal={Journal of cell science},
  volume={106 ( Pt 1)},
Acidosomes are organelles that in Paramecium are responsible for the acidification of phagosomes before phagosomes fuse with lysosomes. Using a combination of (a) the quick-freeze deep-etch (QF-DE) technique, (b) monoclonal antibodies (mAbs) that label specific membrane pools including those of the acidosomes, and (c) horseradish peroxidase (HRP)-uptake studies, we followed the development of acidosomes from the Golgi complex as well as the rapid transfer of HRP into the acidosomes. We also… CONTINUE READING


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