Acidomucin goblet cell expansion induced by parenteral nutrition in the small intestine of piglets.

@article{Conour2002AcidomucinGC,
  title={Acidomucin goblet cell expansion induced by parenteral nutrition in the small intestine of piglets.},
  author={John E Conour and Deshanie Ganessunker and Kelly A. Tappenden and Sharon M Donovan and H. Rex Gaskins},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2002},
  volume={283 5},
  pages={G1185-96}
}
Total parenteral nutrition (TPN) impairs small intestine development and is associated with barrier failure, inflammation, and acidomucin goblet cell expansion in neonatal piglets. We examined the relationship between intestinal goblet cell expansion and molecular and cellular indices of inflammation in neonatal piglets receiving TPN, 80% parenteral + 20% enteral nutrition (PEN), or 100% enteral nutrition (control) for 3 or 7 days. Epithelial permeability, T cell numbers, TNF-alpha and IFN… CONTINUE READING
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