Acidomonas Methanolica-Associated Necrotizing Lymphadenitis in a Patient with Chronic Granulomatous Disease

@article{Chase2012AcidomonasMN,
  title={Acidomonas Methanolica-Associated Necrotizing Lymphadenitis in a Patient with Chronic Granulomatous Disease},
  author={John M. Chase and Steven M Holland and David E. Greenberg and Kimberly R. Marshall-Batty and Adrian M. Zelazny and Joseph A. Church},
  journal={Journal of Clinical Immunology},
  year={2012},
  volume={32},
  pages={1193-1196}
}
Adenitis for which no causative organism can be isolated is a common occurrence in patients with chronic granulomatous disease (CGD). Here we identify Acidomonas methanolica as a pathogen associated with adenitis in a patient with CGD. The causative pathogen was obtained after prolonged incubation of an excised lymph node in thioglycolate broth. Identification was carried out by sequencing the 16s rRNA. Immunoblots were prepared utilizing protein extracts from the case patient’s A. methanolica… CONTINUE READING
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