Acidolin: an antibiotic produced by Lactobacillus acidophilus.

@article{Hamdan1974AcidolinAA,
  title={Acidolin: an antibiotic produced by Lactobacillus acidophilus.},
  author={I. Y. Hamdan and E. M. Mikolajcik},
  journal={The Journal of antibiotics},
  year={1974},
  volume={27 8},
  pages={
          631-6
        }
}
Acidolin was isolated from skimmilk cultured for 48 hours with Lactobacillus acidophilus (CHR. HANSEN's Laboratory strain 2181). It was extracted from the skimmilk with methanol and acetone and was further concentrated and purified by Sephadex G-25 gel filtration, high voltage electrophoresis, and thin-layer chromatography on silica gel. Ultraviolet, infrared, nuclear magnetic resonance, and mass spectra results are presented for the antibiotic. Acidolin has a low molecular weight (-200), is… 
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Studies are reported on the assay of this antibacterial activity, the purification of the substance which appears to be involved, and some of the characteristics of intestinal lactobacilli of man and several common laboratory animals which produce it.
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